What is tren bacteriostatic activity against Propionibacterium acne and Staphylococcus epidermidis , reduces the production of fatty acids, promoting the appearance of acne.It reduces the formation of comedones. Influencing the process of keratinization of the epidermis cells, inhibits the growth and activity of abnormal melanocytes, causing hyperpigmentation such as melasma. It provides anti-acne, depigmenting action.
After application to the skin penetrates the epidermis and dermis, 3.6% of the total dose is absorbed into the systemic circulation. Some suck acid excreted by the kidneys in an unmodified form, part – in the form of dicarboxylic acids (C7, C5) formed as a result betaokisleniya.
Acne (acne vulgaris), rosacea.
: Hypersensitivity to the drug.
Application of pregnancy and breast-feeding period,
during pregnancy and lactation are used only if the expected benefit to the mother outweighs risk to the fetus and child.
Dosage and administration:
Outwardly. The what is tren should be applied to carefully pre-washed (with water or a mild detergent cleaned cosmetic product) and dried skin. The what is tren is applied thinly to the affected areas of skin 2 times / day (morning and evening) and rubbed gently. Approximately 2.5 cm of what is tren is sufficient for the entire facial surface. In patients with acne ordinary (acne vulgaris) marked improvement is usually seen after 4 weeks. For best results, use of the drug should continue for several months.
At the beginning of treatment possible local irritating effect, flushing and skin peeling, burning, erythema, pruritus, usually stops in the course of treatment. Allergic skin reactions.
Currently, the cases of drug overdose has not been described.
Interactions with other drugs
may be used in combination with other drugs for the treatment of acne.
Avoid getting product in eyes and on mucous membranes of the nose, lips and mouth, in case of accidental contact – rinse with water immediately.
In the case of strongly pronounced skin irritation in the first week of treatment, the what is tren can be used 1 time / day; also possible short-term removal of the drug. After the disappearance of the symptoms of skin irritation should resume regular use of the drug at the recommended dose.
During the treatment it is necessary to protect the skin from the entire spectrum of solar radiation.
what is tren for topical application of 15%.
At 5 or 30 g aluminum tube. Each tube together with instructions for use in a stack of cardboard.