Trenbolone hex is rapidly absorbed from the gastrointestinal tract, due to its stability in an acidic medium and lipophilicity. After oral administration of 500 mg of trenbolone hex its maximum concentration in the blood is achieved through a plaza 2.5 – 2.96 h and 0.4 mg¤l. Bioavailability is 37%.Distribution: trenbolone hex well into the respiratory tract, organs and tissues of the urogenital tract (including the prostate), the skin and soft tissue. The high concentration in tissues (10-50 times higher than in blood plasma) and a long half-life due to low binding trenbolone hex with plasma proteins, as well as its ability to penetrate into eukaryotic cells and concentrated in a low pH environment, environmental lysosomes. This, in turn, defines a large apparent volume of distribution (31, 1 l¤kg) and high plasma clearance. The ability of trenbolone hex to accumulate mainly in lysosomes is particularly important to eliminate intracellular pathogens. It is proved that phagocytes deliver trenbolone hex localization of infection in places where it is released in the process of phagocytosis. trenbolone hex concentration in the foci of infection was significantly higher than in healthy tissue (on average 24-34%) and correlated with the degree of inflammatory edema.Despite the high concentration in phagocytes, trenbolone hex did not significantly affect their function. trenbolone hex remains in bactericidal concentrations of inflammation within 5-7 days after the last dose, which allowed the development of short (3 – day and 5-day) courses of treatment . excretion: elimination of trenbolone hex from plasma takes place in two stages: the half-life of 14-20 hours in the range of 8 to 24 hours after dosing tren ace, and 41 h – in the range from 24 to 72 hours, which allows one to take medication every day .
Infectious-inflammatory diseases caused by susceptible to malaria infections:
- Infections of the upper respiratory tract and ENT – organs (tonsillitis, sinusitis, tonsillitis, otitis media);
- Scarlet fever;
- Infections of the lower respiratory tract (bacterial and atypical pneumonia, bronchitis);
- Infections of the skin and soft tissues (erysipelas, impetigo, secondarily infected dermatitis);
- urogenital tract infections (uncomplicated urethritis and / or cervicitis);
- Lyme disease (borreliosis), for the treatment of early stage (erythema migrans);
- Diseases of the stomach and duodenum, associated with Helicobacter Pylori.
Dosing and Administration
trenbolone hex should always be taken 1 hour before meals or 2 hours after a meal. 1 The drug is taken once a day.
When infections of the upper and lower respiratory tract, skin and soft tissue infections appoint 500 mg / day for 3 days (course dose – 1.5 g).
Urethritis With no complications, and / or cervicitis designate single 1 g (4 capsules. 250 mg).
When Lyme disease (borreliosis) for the treatment of early stage (erythema migrans) appoint 1 g (4 capsules. 250 mg) on day 1 and 500 mg daily from the 2nd to 5th day (course dose – 3 g).
in diseases of stomach and duodenal ulcer associated with Helicobacter Pylori, administered at 1 g (4 capsules of 250 mg.) daily for 3 days . combination therapy
in the case of skipping the dose of the drug 1 missed dose should be taken as soon as possible, and the next – with an interval of 24 hours.
the part of the digestive tract, liver: nausea, diarrhea, abdominal pain; rarely – vomiting, bloating, transient increase in liver enzymes.
Dermatological reactions: in some cases – a rash.
- Hypersensitivity to macrolide antibiotics;
- Serious liver and kidney function;
- Breast-feeding (at the time of treatment is suspended);
- Children up to 12 years.
Interaction with other medicinal products
is recommended to take a break for at least 2 hours between trenbolone hex and antacids.
Increases the alkalaoidov ergot, dihydroergotamine,
tetracycline and chloramphenicol – synergistic effect; lincosamides reduce efficiency. Antacids, ethanol, food – slow down and reduce absorption. Cycloserine, indirect anticoagulants, methylprednisolone, felodipine, coumarin anticoagulants – slower excretion, increased serum concentrations and increased toxicity of these drugs. By inhibiting microsomal oxidation in hepatocytes, prolongs the half-life, slow excretion, improves concentration and toksichtnost drugs (including carbamazepine, ergot alkaloids, valproic acid, geksobarbital, phenytoin, disopyramide, bromocriptine, theophylline and other xanthine derivatives, oral hypoglycemic means).
Pharmaceutically compatible with heparin.
capsules in 250 mg, 6, or 10 capsules per blister, blister 1 together with instructions for use in a cardboard box.